New approaches to organocatalysis based on C–H and C–X bonding for electrophilic substrate activation

• Pavel Nagorny and
• Zhankui Sun

Beilstein J. Org. Chem. 2016, 12, 2834–2848, doi:10.3762/bjoc.12.283

• of organocatalysis. While traditional hydrogen bond donors containing N–H and O–H moieties have been effectively used for electrophile activation, activation based on other types of non-covalent interactions is less common. This mini review highlights recent progress in developing and exploring new

• organic catalysts for electrophile activation through the formation of C–H hydrogen bonds and C–X halogen bonds. Keywords: C–H hydrogen bond; counteranion activation; electrophile activation; halogen bond donor; hydrogen bond donor; organocatalysis; Review Introduction Over the past century chemists

• the near future. Electrophile Activation by Hydrogen Bond Donors [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. Early examples of C–H hydrogen bonds and their recent use in supramolecular chemistry [18][19][32][33][34]. Design of 1,2,3-triazole-based catalysts for trityl group transfer